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1

Transformation of a grain legume (Lupinus angustifolius L.) via Agrobacterium tumefaciens-mediated gene transfer to shoot apices

Alix Pigeaire, Deborah Abernethy, Penelope M. Smith, Kaylene Simpson, Natalie Fletcher, Chin-Yi Lu, Craig A. Atkins, Edwina Cornish

Journal:

Molecular Breeding

Year:

1997

Language:

english

File:

PDF, 456 KB

english, 1997

2

Regulation of Cell Adhesion and Collective Cell Migration by Hindsight and Its Human Homolog RREB1

Mariana Melani, Kaylene J. Simpson, Joan S. Brugge, Denise Montell

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 1.36 MB

english, 2008

3

FGFR3 signaling and function in triple negative breast cancer

Chew, Nicole J., Nguyen, Elizabeth V., Su, Shih-Ping, Novy, Karel, Chan, Howard C., Nguyen, Lan K., Luu, Jennii, Simpson, Kaylene J., Lee, Rachel S., Daly, Roger J.

Journal:

Cell Communication and Signaling

Year:

2020

Language:

english

File:

PDF, 5.05 MB

english, 2020

4

The whey acidic protein family: a new signature motif and three-dimensional structure by comparative modeling

Shoba Ranganathan, Kaylene J. Simpson, Denis C. Shaw, Kevin R. Nicholas

Journal:

Journal of Molecular Graphics and Modelling

Year:

1999

Language:

english

File:

PDF, 760 KB

english, 1999

5

Generation of a functional mammary gland from a single stem cell

Shackleton, Mark, Vaillant, François, Simpson, Kaylene J., Stingl, John, Smyth, Gordon K., Asselin-Labat, Marie-Liesse, Wu, Li, Lindeman, Geoffrey J., Visvader, Jane E.

Journal:

Year:

2006

Language:

english

File:

PDF, 699 KB

english, 2006

6

Identification of genes that regulate epithelial cell migration using an siRNA screening approach

Simpson, Kaylene J., Selfors, Laura M., Bui, James, Reynolds, Angela, Leake, Devin, Khvorova, Anastasia, Brugge, Joan S.

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 5.78 MB

english, 2008

7

Brca1 inactivation induces p27Kip1-dependent cell cycle arrest and delayed development in the mouse mammary gland

Deans, Andrew J, Simpson, Kaylene J, Trivett, Melanie K, Brown, Melissa A, McArthur, Grant A

Journal:

Year:

2004

Language:

english

File:

PDF, 494 KB

english, 2004

8

Expression of a Truncated Brca1 Protein Delays Lactational Mammary Development in Transgenic Mice

Melissa A. Brown, Hans Nicolai, Kathy Howe, Toyomasa Katagiri, El-Nasir Lalani, Kaylene J. Simpson, Nathan W. Manning, Andrew Deans, Phil Chen, Kum Kum Khanna, Mas Rina Wati, Beatrice L. Griffiths, Ch

Journal:

Transgenic Research

Year:

2002

Language:

english

File:

PDF, 428 KB

english, 2002

9

The Comparative Biology of Whey Proteins

Kaylene J. Simpson, Kevin R. Nicholas

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2002

Language:

english

File:

PDF, 463 KB

english, 2002

10

Comparative high-throughput RNAi screening methodologies in C. elegans and mammalian cells

Kaylene J. Simpson, Gregory M. Davis, Peter R. Boag

Journal:

New Biotechnology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

11

Differential expression of the whey acidic protein gene during lactation in the brushtail possum (Trichosurus vulpecula)

Jerome Demmer, Susan J. Stasiuk, Murray R. Grigor, Kaylene J. Simpson, Kevin R. Nicholas

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2001

Language:

english

File:

PDF, 568 KB

english, 2001

12

Developmentally-regulated expression of a putative protease inhibitor gene in the lactating mammary gland of the tammar wallaby, Macropus eugenii

Kaylene Simpson, Denis Shaw, Kevin Nicholas

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

13

Differential Remodeling of Actin Cytoskeleton Architecture by Profilin Isoforms Leads to Distinct Effects on Cell Migration and Invasion

Ghassan Mouneimne, Scott D. Hansen, Laura M. Selfors, Lara Petrak, Michele M. Hickey, Lisa L. Gallegos, Kaylene J. Simpson, James Lim, Frank B. Gertler, John H. Hartwig, R. Dyche Mullins, Joan S. Brug

Journal:

Year:

2012

Language:

english

File:

PDF, 4.25 MB

english, 2012

14

Whole-Genome Multiparametric Screening to Identify Modulators of Epithelial-to-Mesenchymal Transition

Said, Nur Akmarina B.M., Gould, Cathryn M., Lackovic, Kurt, Simpson, Kaylene J., Williams, Elizabeth D.

Journal:

Assay and Drug Development Technologies

Year:

2014

Language:

english

File:

PDF, 662 KB

english, 2014

15

Strategies and Challenges for Systematically Mapping Biologically Significant Molecular Pathways Regulating Carcinoma Epithelial-Mesenchymal Transition

Said, Nur Akmarina B.M., Simpson, Kaylene J., Williams, Elizabeth D.

Journal:

Cells Tissues Organs

Year:

2013

Language:

english

File:

PDF, 887 KB

english, 2013

16

High-Content Assay for Measuring Intracellular Growth of Leishmania in Human Macrophages

Dagley, Michael J., Saunders, Eleanor C., Simpson, Kaylene J., McConville, Malcolm J.

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

17

Society of Biomolecular Imaging and Informatics Special Issue

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015

18

Colloquium: SBI 2 HCS/HCA Informatics and Data Analysis - Best Practices and Unmet Needs September 15, 2015

Bowman, Douglas, Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 179 KB

english, 2015

19

Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

Eyre, Nicholas S., Hampton-Smith, Rachel J., Aloia, Amanda L., Eddes, James S., Simpson, Kaylene J., Hoffmann, Peter, Beard, Michael R.

Journal:

Year:

2016

Language:

english

File:

PDF, 17.92 MB

english, 2016

20

Society of Biomolecular Imaging and Informatics Special Issue, November 2015

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

21

Metabolic profiling and in vitro assessment of anthelmintic fractions of Picria fel-terrae Lour.

Kumarasingha, Rasika, Karpe, Avinash V., Preston, Sarah, Yeo, Tiong-Chia, Lim, Diana S.L., Tu, Chu-Lee, Luu, Jennii, Simpson, Kaylene J., Shaw, Jillian M., Gasser, Robin B., Beale, David J., Morrison,

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

22

Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence

Chan, Keefe T., Paavolainen, Lassi, Hannan, Katherine M., George, Amee J., Hannan, Ross D., Simpson, Kaylene J., Horvath, Peter, Pearson, Richard B.

Journal:

Assay and Drug Development Technologies

Year:

2016

Language:

english

File:

PDF, 1.85 MB

english, 2016

23

Isolation, characterisation and hormone-dependent expression of the porcine whey acidic protein

SIMPSON, KAYLENE J, BIRD, PETER, SHAW, DENIS, NICHOLAS, KEVIN

Journal:

Biochemical Society Transactions

Year:

1996

Language:

english

File:

PDF, 106 KB

english, 1996

24

A Phenotypic High-Content Screening Assay to Identify Regulators of Membrane Protein Localization

Smith, Lorey K., Thomas, Daniel W., Simpson, Kaylene J., Humbert, Patrick O.

Journal:

Assay and Drug Development Technologies

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

25

An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

Dutta, Bhaskar, Azhir, Alaleh, Merino, Louis-Henri, Guo, Yongjian, Revanur, Swetha, Madhamshettiwar, Piyush B., Germain, Ronald N., Smith, Jennifer A., Simpson, Kaylene J., Martin, Scott E., Beuhler,

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 4.33 MB

english, 2016

26

Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

Dutta, Bhaskar, Azhir, Alaleh, Merino, Louis-Henri, Guo, Yongjian, Revanur, Swetha, Madhamshettiwar, Piyush B., Germain, Ronald N., Smith, Jennifer A., Simpson, Kaylene J., Martin, Scott E., Buehler,

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 129 KB

english, 2016

27

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

Falkenberg, Katrina J, Gould, Cathryn M, Johnstone, Ricky W, Simpson, Kaylene J

Journal:

Scientific Data

Year:

2014

Language:

english

File:

PDF, 691 KB

english, 2014

28

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

Brasacchio, Daniella, Alsop, Amber E, Noori, Tahereh, Lufti, Mariam, Iyer, Sweta, Simpson, Kaylene J, Bird, Phillip I, Kluck, Ruth M, Johnstone, Ricky W, Trapani, Joseph A

Journal:

Cell Death & Differentiation

Year:

2017

Language:

english

File:

PDF, 1.52 MB

english, 2017

29

SBI 2 HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium

Hoffman, Ann F., Simpson, Kaylene J., Horvath, Peter, Lovitt, Carrie, Silver, Serena, Easton, Evan, LaBarbera, Daniel V., Mendez, Melissa, Rothenberg, Mark E., Seldin, Jan, Wardwell-Swanson, Judi, Fen

Journal:

Assay and Drug Development Technologies

Year:

2017

Language:

english

File:

PDF, 230 KB

english, 2017

30

Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology

Williams, Steven P., Gould, Cathryn M., Nowell, Cameron J., Karnezis, Tara, Achen, Marc G., Simpson, Kaylene J., Stacker, Steven A.

Journal:

Scientific Data

Year:

2017

Language:

english

File:

PDF, 937 KB

english, 2017

31

Signalome-wide assessment of host cell response to hepatitis C virus

Haqshenas, Gholamreza, Wu, Jianmin, Simpson, Kaylene J., Daly, Roger J., Netter, Hans J., Baumert, Thomas F., Doerig, Christian

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 690 KB

english, 2017

32

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes

Preston, Sarah, Jiao, Yaqing, Baell, Jonathan B., Keiser, Jennifer, Crawford, Simon, Koehler, Anson V., Wang, Tao, Simpson, Moana M., Kaplan, Ray M., Cowley, Karla J., Simpson, Kaylene J., Hofmann, An

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2017

Language:

english

File:

PDF, 2.81 MB

english, 2017

33

Trypanosome RNA Editing Mediator Complex proteins have distinct functions in gRNA utilization

Simpson, Rachel M., Bruno, Andrew E., Chen, Runpu, Lott, Kaylen, Tylec, Brianna L., Bard, Jonathan E., Sun, Yijun, Buck, Michael J., Read, Laurie K.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 6.53 MB

english, 2017

34

Knocking down the obstacles to functional genomics data sharing

Simpson, Kaylene J., Smith, Jennifer A.

Journal:

Scientific Data

Year:

2017

Language:

english

File:

PDF, 123 KB

english, 2017

35

A Functional Kinase Short Interfering Ribonucleic Acid Screen Using Protease-Activated Receptor 2-Dependent Opening of Transient Receptor Potential Vanilloid-4

Darby, William G., Grace, Megan S., Simpson, Kaylene J., Woodman, Owen L., McIntyre, Peter

Journal:

Assay and Drug Development Technologies

Year:

2017

Language:

english

File:

PDF, 809 KB

english, 2017

36

Discovering cancer vulnerabilities using high-throughput micro-RNA screening

Nikolic, Iva, Elsworth, Benjamin, Dodson, Eoin, Wu, Sunny Z., Gould, Cathryn M., Mestdagh, Pieter, Marshall, Glenn M., Horvath, Lisa G., Simpson, Kaylene J., Swarbrick, Alexander

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

37

Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

Jiao, Yaqing, Preston, Sarah, Koehler, Anson V., Stroehlein, Andreas J., Chang, Bill C. H., Simpson, Kaylene J., Cowley, Karla J., Palmer, Michael J., Laleu, Benoît, Wells, Timothy N. C., Jabbar, Abdu

Journal:

Parasites & Vectors

Year:

2017

Language:

english

File:

PDF, 919 KB

english, 2017

38

Optimized PCR Conditions and Increased shRNA Fold Representation Improve Reproducibility of Pooled shRNA Screens

Strezoska, Žaklina, Licon, Abel, Haimes, Josh, Spayd, Katie Jansen, Patel, Kruti M., Sullivan, Kevin, Jastrzebski, Katarzyna, Simpson, Kaylene J., Leake, Devin, van Brabant Smith, Anja, Vermeulen, Ann

Journal:

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

39

Society of Biomolecular Imaging and Informatics Special Issue

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2018

Language:

english

File:

PDF, 71 KB

english, 2018

40

Society of Biomolecular Imaging and Informatics Special Issue, October 2016

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2016

Language:

english

File:

PDF, 59 KB

english, 2016

41

Society of Biomolecular Imaging and Informatics Special Issue

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2016

Language:

english

File:

PDF, 64 KB

english, 2016

42

Society of Biomolecular Imaging and Informatics Special Issue

Fennell, Myles, Simpson, Kaylene J.

Journal:

Assay and Drug Development Technologies

Year:

2017

File:

PDF, 68 KB

2017

43

Requirement for cleavage factor IIm in the control of alternative polyadenylation in breast cancer cells

Turner, Rachael E, Henneken, Lee M, Liem-Weits, Marije, Harrison, Paul F, Swaminathan, Angavai, Vary, Robert, Nikolic, Iva, Simpson, Kaylene J, Powell, David R, Beilharz, Traude, Dichtl, Bernhard

Journal:

Year:

2020

File:

PDF, 2.19 MB

2020

44

Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen

Bhatia, Sugandha, Blick, Tony, Pinto, Cletus, Waltham, Mark, Monkman, James, Ivanova, Ekaterina, Pollock, Pamela M., Nagaraj, Shivashankar H., Wiegmans, Adrian P., Haviv, Izhak, Simpson, Kaylene J., T

Journal:

Year:

2020

File:

PDF, 1.42 MB

2020

45

Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex

Sharp, Michael F., Murphy, Vince J., Twest, Sylvie Van, Tan, Winnie, Lui, Jennii, Simpson, Kaylene J., Deans, Andrew J., Crismani, Wayne

Journal:

Scientific Reports

Year:

2020

File:

PDF, 2.87 MB

2020

46

GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma

Gotovac, Jovana R., Liu, David S.H., Yates, Michael J., Milne, Julia V., Macpherson, Arthi A., Simpson, Kaylene J., Eslick, Guy D., Mitchell, Catherine, Duong, Cuong P., Phillips, Wayne A., Clemons, N

Journal:

The Journal of Pathology

Year:

2020

File:

PDF, 4.00 MB

2020

47

Loss of HPV type 16 E7 restores cGAS-STING responses in human papilloma virus-positive oropharyngeal squamous cell carcinomas cells

Bortnik, Vuk, Wu, Michelle, Julcher, Bryan, Salinas, Ana, Nikolic, Iva, Simpson, Kaylene J., McMillan, Nigel AJ., Idris, Adi

Journal:

Journal of Microbiology, Immunology and Infection

Year:

2020

File:

PDF, 666 KB

2020

48

Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAFV600 melanoma cells

Smith, Lorey K., Parmenter, Tiffany, Gould, Cathryn M., Madhamshettiwar, Piyush B., Sheppard, Karen E., Simpson, Kaylene J., McArthur, Grant A.

Journal:

Scientific Data

Year:

2020

File:

PDF, 2.67 MB

2020

49

Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen

King, Lauren E., Zhang, Hui-Hua, Gould, Cathryn M., Thomas, Daniel W., Whitehead, Lachlan W., Simpson, Kaylene J., Burgess, Antony W., Faux, Maree C., Liu, Chunming

Journal:

Year:

2020

File:

PDF, 2.25 MB

2020

50

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

Yan, Shunfei, Xuan, Jiachen, Brajanovski, Natalie, Tancock, Madeleine R. C., Madhamshettiwar, Piyush B., Simpson, Kaylene J., Ellis, Sarah, Kang, Jian, Cullinane, Carleen, Sheppard, Karen E., Hannan,

Journal:

British Journal of Cancer

Year:

2020

File:

PDF, 4.44 MB

2020